Essay On Breast Cancer - 1547 Words

Breast Cancer In 2016, breast cancer was the commonest diagnosed cancer in women with 17 million cases diagnosed and a resultant 5 million deaths. In the Western world, improved treatments and screening programmes have resulted in a 5-year survival of 80-90% (WHO, 2016). However, a third of breast cancer patients are found to have distant metastases at diagnosis, bringing their 5-year survival rate down by 25% (Siegel et al., 2004). Metastasis occurs when tumour cells travel through the vascular or lymphatic system and grow in distant organs, commonly bone, lung, liver and brain. Current treatment involves surgical removal of the visible tumour bulk followed by chemo- and radio- therapy targeting distant spread. Breast cancer is†¦show more content†¦Tumour Micro-environment The tumour stroma appears to be a major factor in tumour progression after initial tumour formation (Conklin and Keely, 2007). It initially protects against tumourigenesis; but neoplastic cells cause changes and recruit various other cell lines with a multitude of functions, forming a tumour micro-environment (TME). This is defined as â€Å"a heterogeneous population of cells consisting of the tumor bulk plus supporting cells† (Bussard et al., 2006). The tumour cells recruit the stroma cells and cause a reactive phenotype, known as tumor-associated stromal cells (TASCs). Mesenchymal stem cells, endothelial cells, pericytes, fibroblasts and various other immune cells are all components of the TME,each with specific functions. When activated, they take on a similar in function to those found in inflammation and wound healing and cause fibroblast infiltration, recruitment of immune cells, remodelling of the extracellular matrix. This is why cancer has been likened to a wound that never heals, the tumour stroma being chronically activated and promoting growth and angiogenesis (Dvorak, 1984). The rapid proliferation of tumour cells soon exhausts the existing vascular supply and brings about a hypoxic environment in the TME (Coussens and Werb, 2005). Endothelial and stromal cells form aShow MoreRelated Breast Cancer Essay1204 Words   |  5 Pages BREAST CANCER I) Anatomy of the breast nbsp;nbsp;nbsp;nbsp;nbsp;The breast is a gland designed to make milk. nbsp;nbsp;nbsp;nbsp;nbsp; II) What is breast cancer? nbsp;nbsp;nbsp;nbsp;nbsp;Breast cancer is an abnormal growth of cells. nbsp;nbsp;nbsp;nbsp;nbsp;These abnormal growths are called tumors. Not all tumors are cancerous. nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;Non-cancerous tumors – benign nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;CancerousRead More Breast Cancer Essay985 Words   |  4 Pages Breast Cancer: Risk Factors, Detection amp; Treatment nbsp;nbsp;nbsp;nbsp;nbsp;Among all American women who die when they are between the ages of forty and forty-five, the cause of death most likely to be listed on their death certificates is BREAST CANCER. Breast tumors are responsible for the greatest number of deaths among women, and breast cancer alone is the cause of almost one fifth of all cancer related mortalities. It results in the death of thirty seven thousand American womenRead More breast cancer Essay1111 Words   |  5 Pages Breast Cancer nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;nbsp;Breast cancer is the most common cancer among women. 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It isRead MoreBreast Cancer Essay965 Words   |  4 PagesBreast cancer exists today as a vicious disease which has multiple facets for killing its host. The largest indicator of survival rate is length of time alive after diagnosis with the disease, and then whether or not the disease has metastasized to a new location in the body. For breast cancer patients, the 5-year surviv al rate of patients below Stage 4 is 90%. The stages below the 4 stage represent the stages where the breast cancer has not metastasized into other regions of the body. When breastRead MoreBreast Cancer Essay992 Words   |  4 Pagesdeveloping breast cancer, there presence alone does not always result in breast cancer. The two genes that are indicative of breast cancer are BRCA1 and BRCA2. However, these genes are not the only indicators of breast cancer, although, there presence carries the greatest chance of development. The other genes that also serve as indicators of possible breast cancer are CHEK2, PTEN, TP53, PALB2, STK11, and CDH1. These genes are extremely significant because the presence or absence of a mutation formRead MoreMale Breast Cancer Essay861 Words   |  4 Pages Breast cancer in males is quite common, yet still many people are unaware of this disease. Often, it can go undiagnosed until the cancer is in the fourth stage. Every year over 2,000 men will be diag nosed, but only 54% will survive. Cancer in men is often overlooked as it is almost 100 times less common in men than women. During a man’s entire lifespan, the risk of having a diagnosis is about one in one-thousand. The most common symptom of this devastating disease are a lump or some swelling. ThisRead More Breast Cancer Essay1298 Words   |  6 PagesBreast Cancer There is a large amount of women who are diagnosed with breast cancer every day but they usually do not know a lot about it in terms of how it forms and the many ways it can be treated. Breast cancer is a very serious disease that shouldn’t be taken lightly; if it is left untreated it can spread to other organs and eventually kill you.   Even if you do not have breast cancer, chances are that you know or will know someone who will get it, so it is imperative that people understandRead More Breast Cancer Essay1235 Words   |  5 PagesBreast Cancer Cancer is one of the leading causes of death in the United States. There are many different types of cancer that are affecting people all over. Breast Cancer is one of these, and is found in man and women. Over 200,000 women and 1,300 men have been diagnosed with breast cancer this year. One in eight women will detect breast cancer in their lifetime. Men are less than one percent of the cases of breast cancer that are detected. Although prevention is not yet available, earlyRead More Breast Cancer Essay907 Words   |  4 Pages Breast cancer is a frightening disease. It can be fatal, and while two thirds of the cases occur among mature women, it also strikes younger females and about nine thousand males each year. The fear generated by breast cancer is intensified by the somewhat shocking reality that breast cancer has actually increased over the last fifty years. In 1940, a woman had a one-in-twenty chance of developing the disease, while today one out of every eight women w ill get breast cancer. According to the National

Definition Of Applied Behavior Analysis Essay - 1554 Words

Introduction Autism is a disease that is being diagnosed today more than ever before. In fact, as of 2014 the statistics for diagnosis of autism are one in sixty-eight children, with diagnosis being much more common in boys (Autism Speaks, 2016a). While there are many theories about what causes autism, there is currently not any proven predictor of what will cause this disease to develop (Landrigan, 2010). Since prevention is not possible at this time, it is extremely beneficial and important to research understanding and treatment of those diagnosed with Autism Spectrum Disorder (ASD). There are many avenues of treatment for ASD, but one method that has received significant attention is applied behavior analysis (ABA). The goal of this research article is to explore the definition of applied behavior analysis, its development over time, and its application to real life. Some questions that will be explored are when and where did ABA originate, how has it developed over time, and what researchers contributed new findings to this intervention. Additionally, the methods that have been developed over time to implement ABA will be discussed, specifically with their application to autism and individuals diagnosed with ASD. Finally, there will be a discussion of how skills that individuals with ASD gain from applied behavioral analysis can be applied to a classroom setting. History Applied behavior analysis has origins in the research done by behaviorist psychologistsShow MoreRelatedUse of Applied Behavior Analysis to Support Language Development in Children with Autism1508 Words   |  7 PagesApplied Behavior Analysis (ABA) is the science in which tactics derived from the principles of behavior are applied systematically to improve socially significant behavior and experimentation is used to identify the variables responsible for behavior change. 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It was originally known as historical materialism which is â€Å"a critical analysis of capitalism that saw the material or economic basis of inequality and power relationsRead MoreHacking And The Social Learning Theory1365 Words   |  6 Pagesresponsible for the onset of the behavior rather than a continuation of the behavior (Morris Higgins, 2010). Definitions refer to the influence of factors with one’s having fdefine the appriateness f an act. This involves one’s rationalization, neutralizations, justifications, and excuses toward engaging in a certain behavior. The more someone has learned and approves of definitions favorable to deviance, the more likely they will participate in that behavior (Morris Higgins, 2010). HackingRead MoreWhat I Have Learned About Research1270 Words   |  6 PagesI also learned the difference between basic and applied research where basic research focuses mostly on things such as emotion, cognition, social behavior, personality development, learning, and neuropsychology. Basic research will be more helpful for answering fundamental questions about the nature of behavior. Applied research however, addresses more of a specific problem with a possible solution. Program evaluation covers a large area of applied research. Program evaluation assesses the socialRead MoreThe Concept Analysis of Stress in the Nursing Field980 Words   |  4 PagesConcept Analysis of Stress: The nursing field is an occupation that is naturally subject to a high degree of stress because professionals in this field deal with grief, suffering, and death cases. The vulnerability to stress in the nursing occupation is also fueled by the fact that several nursing tasks tend to be mundane and unrewarding. 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How feasible are the theories outlined above? Are some parts in the process more important than others? If so, which parts? Martin Fishbein and Icek Ajzen developed the Theory of Reasoned Action (1975, 1980). â€Å"This resulted from attitude research from the Expectancy Value Models. Ajzen and Fishbein formulated the TRA after trying toRead MoreDescriptive Research Method1058 Words   |  5 PagesDescriptive Research Methods (Ch. 12) Case Studies: Detailed analysis of a single (or limited number) of people or events. Case studies are usually interesting because of the unusualness of the case (Three Faces of Eve, Mind of a Mnemonist) and/or the detail and apparent insightfulness of the conclusions drawn by the writer (e.g., Freud’s cases such as ‘Little Hans’). The major problem with case studies is the problem of objectivity. The person who is presenting the case usually has some theoreticalRead MoreSoftware Engineering : An Intrinsic Property Of Software1285 Words   |  6 Pagesthe external behavior of the code, yet improves its internal structure†. The key idea here is to redistribute classes, variables, and methods across the class hierarchy in order to facilitate future adaptations and extensions. The refactoring process consists of a number of distinct activities: ïÆ'Ëœ Identify where the software should be refactored. ïÆ'Ëœ Determine which refactoring(s) should be applied to the identified places. ïÆ'Ëœ Guarantee that the applied refactoring preserves behavior. ïÆ'Ëœ Apply the refactoring

Froogle V. Mary Ccp 410.10 Free Essays

Relevant Facts Our Client, Froogle (â€Å"Froogle†) has retained our firm to file suit againt Mary, a small manufacturer and retailer of downhill snow skis. Froogle and Mary signed an agreement in January of 2012. On or about March 15, 2012 Froogle discovered that Mary had breached several of the terms of their agreement. We will write a custom essay sample on Froogle V. Mary Ccp 410.10 or any similar topic only for you Order Now We filed suit in Superior Court for the County of Monterey in Salinas, California on behalf of Froogle on May 31,2012. Mary, a resident of Vermont, responded by filing a motion for non-conveniens claiming that because her business and residence are in Vermont, California has no jurisdiction over her. Mary violated the terms of her agreement and should be brought to answer for her actions in a California court of law, as Froogle’s main place of business is Salinas, California. Issue Presented The issue is whether or not Froogle has jurisdiction over Mary who is an out of state resident and business owner. Applicable Law Under the California Code of Civil Procedure â€Å"A court of this state may exercise jurisdiction on any basis not inconsistent with the Constitution of this state or of the United States. † CCP  §410. 10 Also known as California’s â€Å"Long Arm Statue† the law provides that the use is usually constitutional â€Å"where the defendant has certain minimum contacts with the forum state and there has been reasonable notice of the action against him or her. (Cite) Additionally, under the ruling â€Å"Any person may maintain an action or proceeding in a court of this state against a foreign corporation or nonresident person where the action or proceeding arises out of or relates to any contract, agreement, or undertaking for which a choice of California law has been made in whole or in part by the parties thereto and which (a) is a contract, agreement, or undertaking, contingent or otherwise, relating to a transaction involving in the aggregate not less than one million dollars ($1,000,000), and (b) contains a provision or provisions under which the foreign corporation or nonresident agrees to submit to the jurisdiction of the courts of this state. † In 9th Circuit Court of Appeals Gator. com Corp. , Plaintiff-appellant, v. L. L. Bean, Inc. , Defendant, appelee, L. L. Bean had an internet catalog and mail order site or a â€Å"virtual store†. Court held that LL Bean’s marketing and retail activities and â€Å"virtual store † created a â€Å"consistent and substantial pattern of business relations in California, sufficient to confer personal jurisdiction over the Maine-based company [Gator}. † In Pavlovich v. Superior Court, the court addressed the issue of internet and jurisdiction holding that â€Å"[t]he Internet, as a mode of communication and a system of information delivery is new, but the rules governing the protection of property rights, and how that protection may be enforced under the new technology, need not be. † 2001 Cal. App. LEXIS 623 (Cal. Ct. App. August 7, 2001) However, in Zippo Mfg. Co. v. Zippo Dot Com, Inc. , the court determined that â€Å"A passive website that does little more than make information available is not generally grounds for the exercise of personal jurisdiction. † It then goes on to say that â€Å"The middle ground is occupied by the interactive websites where a user can exchange information with the host computer. (Zippo test cases) 957 F. Supp. 1119 (W. D. Pa. 1997). The middle ground definition cited above is key in Froogle’s case because Froogle was not simply a passive website. Users were able to click on the Froogle â€Å"store† and search for items. The store then quoted pricing and directed the user to the defendant’s website or alternatively they could purchase through Froogle, using their credit card or other financing available and Froogle would forward the order to the defendant to fulfill the order. In Frank Snowney v. Harrahs the plaintiff reserved a room by telephone from his California residence. He was told that the room would cost $50/night plus tax. When he received the bill he paid a $3 energy surcharge. Plaintiff filed a class action against Harrahs alleging they charged him and other guests more than the advertised price†¦. † The defendants filed a motion to quash for lack of personal jurisdiction, arguing that they were incorporated and based out of Nevada, they conducted no business in California and had no bank accounts in California. The plaintiff submitted that â€Å"the defendants 1-advertised extensively to California residents through billboards in California, newspapers and radio television; 2) maintained an interactive website that accepted reservations from California residents. The Court concluded that defendants had sufficient contacts in California to justify jurisdiction in the state. 116 Cal. App. 4th 996, (2004). Application to Our Case Froogle is a California corporation with home offices in Salinas, California. Froogle’s contract was signed by the defendant and the defendant was well awa re of Froogle’s location. Froogle’s software was developed in California and their servers are all located in various parts of California – Froogle is clearly a California product. As the defendant used online transactions through Froogle’s site to set up their account and perform other implementation functions it can be easily argued that this was a California based transaction. Further to this, the defendant benefitted from Froogle’s high profile in California, expanding their customer base throughout the state and thus increasing their sales. The California Code protects Froogle’s right to jurisdiction in California under the â€Å"Long Arm† statute. Although there are rare circumstances where this can be overturned, the statute provides the ability for a California corporation that has entered under a contract or similar document with a non-resident partner to gain jurisdiction over that entity should breach of that contract occur. The Snowney case more than implies that if one enters into an agreement with a California entity, and a breach or other violation of the agreement occurs, the parties will more than likely be bringing their action to a California court. The reservation can certainly be interpreted to be a contract as it binds both parties to an obligation and by acceptance of the terms of a reservation, the parties have entered into an agreement or contract. Froogle has the right as a California corporation to file their action in the state of California. The defendant knew it was entering into a contract with a California corporation based out of Salinas, CA. The defendant chose the website due to its power in the retail internet market. It also took advantage of the plaintiff’s website store which brought leads to the defendants store from prospective customers. The defendant’s business benefitted greatly from its presence in the plaintiff’s search engine and webstore. The defendant has no right to jurisdiction in this case and this proceeding should continue in California. How to cite Froogle V. Mary Ccp 410.10, Essay examples